Version 5.4
Homo sapiens Protein: IL24
Summary
InnateDB Protein IDBP-106287.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL24
Protein Name interleukin 24
Synonyms C49A; FISP; IL10B; MDA7; MOB5; ST16;
Species Homo sapiens
Ensembl Protein ENSP00000294984
InnateDB Gene IDBG-106283 (IL24)
Protein Structure
UniProt Annotation
Function Has antiproliferative properties on melanoma cells and may contribute to terminal cell differentiation.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Up-regulated in melanoma cells induced to terminally differentiate.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 8 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 1 [view]
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
Biological Process
GO:0006915 apoptotic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR009079 Four-helical cytokine-like, core
IPR020444 Interleukin-24
PFAM
PRINTS PR01937
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q13007
PhosphoSite PhosphoSite-Q13007
TrEMBL
UniProt Splice Variant
Entrez Gene 11009
UniGene Hs.741469
RefSeq NP_006841
HUGO HGNC:11346
OMIM 604136
CCDS CCDS1471
HPRD 04995
IMGT
EMBL AC098935 AF235005 AF276916 AY062931 AY237723 AY641441 BC009681 BT007156 U16261
GenPept AAA91780 AAG41401 AAH09681 AAK52589 AAL34146 AAO67513 AAP35820 AAV52801

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca