InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RPS6KC1

Summary

InnateDB Protein

IDBP-106630.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPS6KC1

Protein Name

ribosomal protein S6 kinase, 52kDa, polypeptide 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000355926

InnateDB Gene

IDBG-106626 (RPS6KC1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	5 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0035091	phosphatidylinositol binding

Biological Process

GO:0006468	protein phosphorylation
GO:0007165	signal transduction

Cellular Component

GO:0005737	cytoplasm
GO:0005769	early endosome
GO:0016020	membrane
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001683 Phox homologous domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR007330 MIT
IPR011009 Protein kinase-like domain

PFAM

PF00069
PF07714
PF00787
PF04212

PRINTS

PR00109

PIRSF

SMART

SM00312
SM00220
SM00745

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt