InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: WNT9A

Summary

InnateDB Protein

IDBP-107119.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

WNT9A

Protein Name

wingless-type MMTV integration site family, member 9A

Synonyms

WNT14;

Species

Homo sapiens

Ensembl Protein

ENSP00000272164

InnateDB Gene

IDBG-107115 (WNT9A)

Protein Structure

UniProt Annotation

Function

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted, extracellular space, extracellular matrix.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005109	frizzled binding
GO:0005515	protein binding

Biological Process

GO:0007093	mitotic cell cycle checkpoint
GO:0007267	cell-cell signaling
GO:0007275	multicellular organismal development
GO:0008285	negative regulation of cell proliferation
GO:0016055	Wnt signaling pathway
GO:0030182	neuron differentiation
GO:0032331	negative regulation of chondrocyte differentiation
GO:0035115	embryonic forelimb morphogenesis
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045165	cell fate commitment
GO:0045597	positive regulation of cell differentiation
GO:0045880	positive regulation of smoothened signaling pathway
GO:0048704	embryonic skeletal system morphogenesis
GO:0048856	anatomical structure development
GO:0060070	canonical Wnt signaling pathway
GO:0060548	negative regulation of cell death
GO:0061037	negative regulation of cartilage development
GO:0061072	iris morphogenesis
GO:0061303	cornea development in camera-type eye
GO:0071300	cellular response to retinoic acid
GO:0072498	embryonic skeletal joint development