InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TAF5L

Summary

InnateDB Protein

IDBP-107336.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TAF5L

Protein Name

TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000355636

InnateDB Gene

IDBG-107334 (TAF5L)

Protein Structure

UniProt Annotation

Function

Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex.

Subcellular Localization

Nucleus {ECO:0000269PubMed:11564863, ECO:0000269PubMed:9674425}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.

Experimentally validated
Total	28 [view]
Protein-Protein	28 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003713	transcription coactivator activity
GO:0004402	histone acetyltransferase activity
GO:0005515	protein binding

Biological Process

GO:0006325	chromatin organization
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0043966	histone H3 acetylation