InnateDB Protein
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IDBP-107340.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TAF5L
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Protein Name
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TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000355635
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InnateDB Gene
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IDBG-107334 (TAF5L)
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Protein Structure
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Function |
Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:11564863, ECO:0000269PubMed:9674425}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
28
[view]
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Protein-Protein |
28
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0003713
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transcription coactivator activity
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GO:0004402
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histone acetyltransferase activity
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GO:0005515
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protein binding
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001680
WD40 repeat
IPR007582
TFIID subunit, WD40-associated region
IPR017986
WD40-repeat-containing domain
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PFAM |
PF00400
PF04494
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PRINTS |
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PIRSF |
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SMART |
SM00320
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TIGRFAMs |
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Modification |
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SwissProt |
O75529
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PhosphoSite |
PhosphoSite-O75529
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
27097
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UniGene |
Hs.721304
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RefSeq |
NP_001020418
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HUGO |
HGNC:17304
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OMIM |
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CCDS |
CCDS31051
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HPRD |
11619
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IMGT |
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EMBL |
AF069736
AJ009770
AL121990
BC041094
CH471098
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GenPept |
AAC39906
AAH41094
CAA08816
CAI22015
CAI22016
EAW69902
EAW69903
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