Version 5.4
Homo sapiens Protein: COG2
Summary
InnateDB Protein IDBP-107362.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COG2
Protein Name component of oligomeric golgi complex 2
Synonyms LDLC;
Species Homo sapiens
Ensembl Protein ENSP00000355628
InnateDB Gene IDBG-107358 (COG2)
Protein Structure
UniProt Annotation
Function Required for normal Golgi morphology and function.
Subcellular Localization Golgi apparatus membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008565 protein transporter activity
Biological Process
GO:0006486 protein glycosylation
GO:0006886 intracellular protein transport
GO:0006891 intra-Golgi vesicle-mediated transport
GO:0007030 Golgi organization
GO:0009312 oligosaccharide biosynthetic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005795 Golgi stack
GO:0017119 Golgi transport complex
Protein Structure and Domains
PDB ID
InterPro IPR024602 Conserved oligomeric Golgi complex, subunit 2, N-terminal
IPR024603 COG complex component, COG2, C-terminal
PFAM PF06148
PF12022
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14746
PhosphoSite PhosphoSite-Q14746
TrEMBL
UniProt Splice Variant
Entrez Gene 22796
UniGene Hs.719359
RefSeq NP_001138508
HUGO HGNC:6546
OMIM 606974
CCDS CCDS44329
HPRD 07372
IMGT
EMBL AL158214 BC014960 BC051906 CH471098 Z34975
GenPept AAH14960 AAH51906 CAA84427 CAI15359 EAW69916

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca