Version 5.4
Homo sapiens Protein: KCTD5
Summary
InnateDB Protein IDBP-10818.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCTD5
Protein Name potassium channel tetramerisation domain containing 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000301738
InnateDB Gene IDBG-10816 (KCTD5)
Protein Structure
UniProt Annotation
Function Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4.
Subcellular Localization Cytoplasm, cytosol. Nucleus. Note=Predominantly cytoplasmic, translocated to the nucleus upon interaction with Rep proteins.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0032403 protein complex binding
Biological Process
GO:0016032 viral process
GO:0051260 protein homooligomerization
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR003131 Potassium channel tetramerisation-type BTB domain
IPR011333 BTB/POZ fold
PFAM PF02214
PRINTS
PIRSF
SMART SM00225
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NXV2
PhosphoSite PhosphoSite-Q9NXV2
TrEMBL
UniProt Splice Variant
Entrez Gene 54442
UniGene Hs.61960
RefSeq NP_061865
HUGO HGNC:21423
OMIM 611285
CCDS CCDS10475
HPRD 13768
IMGT
EMBL AK000047 BC007314 CH471112
GenPept AAH07314 BAA90906 EAW85489 EAW85491

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca