InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PAPLN

Summary

InnateDB Protein

IDBP-11361.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PAPLN

Protein Name

papilin, proteoglycan-like sulfated glycoprotein

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000345395

InnateDB Gene

IDBG-11359 (PAPLN)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Secreted {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004222	metalloendopeptidase activity
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006508	proteolysis
GO:0010951	negative regulation of endopeptidase activity

Cellular Component

GO:0005604	basement membrane
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

InterPro

IPR000884 Thrombospondin, type 1 repeat
IPR002223 Proteinase inhibitor I2, Kunitz metazoa
IPR003596 Immunoglobulin V-set, subgroup
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR010294 ADAM-TS Spacer 1
IPR010909 PLAC
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
IPR013273 Peptidase M12B, ADAM-TS

PFAM