InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZSCAN10

Summary

InnateDB Protein

IDBP-11568.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZSCAN10

Protein Name

zinc finger and SCAN domain containing 10

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000252463

InnateDB Gene

IDBG-11566 (ZSCAN10)

Protein Structure

UniProt Annotation

Function

Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can both activate and /or repress expression of target genes, depending on the context. Specifically binds the 5'-[GA]CGCNNGCG[CT]-3' DNA consensus sequence. Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4 (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00187}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0045892	negative regulation of transcription, DNA-templated