Version 5.4
Homo sapiens Protein: PNMA1
Summary
InnateDB Protein IDBP-11631.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PNMA1
Protein Name paraneoplastic antigen MA1
Synonyms MA1;
Species Homo sapiens
Ensembl Protein ENSP00000318914
InnateDB Gene IDBG-11629 (PNMA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus, nucleolus {ECO:0000269PubMed:10050892}. Note=In tumor cells, it is cytoplasmic.
Disease Associations
Tissue Specificity Testis- and brain-specific. In some cancer patients, specifically expressed by paraneoplastic tumor cells. {ECO:0000269PubMed:10050892, ECO:0000269PubMed:19366867}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
Experimentally validated
Total 29 [view]
Protein-Protein 26 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002437 inflammatory response to antigenic stimulus
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005925 focal adhesion
Protein Structure and Domains
PDB ID
InterPro IPR009050 Globin-like
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8ND90
PhosphoSite PhosphoSite-Q8ND90
TrEMBL
UniProt Splice Variant
Entrez Gene 9240
UniGene Hs.194709
RefSeq NP_006020
HUGO HGNC:9158
OMIM 604010
CCDS CCDS9818
HPRD 04926
IMGT
EMBL AF037364 AF320308 AK290980 AL834327 BC039577 CH471061
GenPept AAD13810 AAH39577 AAN05100 BAF83669 CAD38995 EAW81126

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca