InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZNF263

Summary

InnateDB Protein

IDBP-11803.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZNF263

Protein Name

zinc finger protein 263

Synonyms

FPM315; ZKSCAN12; ZSCAN44;

Species

Homo sapiens

Ensembl Protein

ENSP00000219069

InnateDB Gene

IDBG-11801 (ZNF263)

Protein Structure

UniProt Annotation

Function

Might play an important role in basic cellular processes as a transcriptional repressor.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00187}.

Disease Associations

Tissue Specificity

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0045892	negative regulation of transcription, DNA-templated

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0015630	microtubule cytoskeleton

Protein Structure and Domains

PDB ID

InterPro

IPR001909 Krueppel-associated box
IPR003309 Transcription regulator SCAN
IPR007087 Zinc finger, C2H2
IPR008916 Retrovirus capsid, C-terminal
IPR015880 Zinc finger, C2H2-like

PFAM

PF01352
PF02023
PF00096

PRINTS

PIRSF

SMART

SM00349
SM00431
SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O14978