Version 5.4
Homo sapiens Protein: ZNF253
Summary
InnateDB Protein IDBP-11823.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF253
Protein Name zinc finger protein 253
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000347868
InnateDB Gene IDBG-547266 (ZNF253)
Protein Structure
UniProt Annotation
Function May function as a transcription factor. Seem to have a transcriptional repression activity.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in bone marrow and in monocytic and immature erythroid cell lines.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O75346
PhosphoSite PhosphoSite-O75346
TrEMBL
UniProt Splice Variant
Entrez Gene 56242
UniGene Hs.735432
RefSeq
HUGO HGNC:13497
OMIM 606954
CCDS
HPRD 06093
IMGT
EMBL AC011477 AF038951 AK074757 AK074872 BC014148 BC065572 BC125063 BC125064
GenPept AAC26844 AAH14148 AAH65572 AAI25064 AAI25065 BAC11185 BAC11257

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca