Homo sapiens Protein: CRELD2
Summary
InnateDB Protein IDBP-12637.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CRELD2
Protein Name cysteine-rich with EGF-like domains 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000332223
InnateDB Gene IDBG-12635 (CRELD2)
Protein Structure
UniProt Annotation
Function May regulate transport of alpha4-beta2 neuronal acetylcholine receptor.
Subcellular Localization Secreted {ECO:0000305}. Endoplasmic reticulum {ECO:0000269PubMed:16238698}.
Disease Associations
Tissue Specificity Ubiquitously expressed. {ECO:0000269PubMed:16238698, ECO:0000269PubMed:16919896}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
Experimentally validated
Total 36 [view]
Protein-Protein 35 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005783 endoplasmic reticulum
Protein Structure and Domains
PDB ID
InterPro IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR006212 Furin-like repeat
IPR009030 Insulin-like growth factor binding protein, N-terminal
IPR021852 Domain of unknown function DUF3456
PFAM PF00008
PF07645
PF11938
PRINTS
PIRSF
SMART SM00181
SM00179
SM00261
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6UXH1
PhosphoSite PhosphoSite-Q6UXH1
TrEMBL A6PWM2
UniProt Splice Variant
Entrez Gene 79174
UniGene Hs.211282
RefSeq NP_077300
HUGO HGNC:28150
OMIM 607171
CCDS CCDS14082
HPRD 08455
IMGT
EMBL AJ968414 AL671710 AY358355 BC002894 BC050675 CH471138 DQ470676 DQ470677 DQ470678 DQ470679 DQ470680
GenPept AAH02894 AAH50675 AAQ88721 ABF06668 ABF06669 ABF06670 ABF06671 ABF06672 CAI91316 CAO72066 CAO72067 CAO72068 CAO72069 EAW73483 EAW73484