InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rbmy1a1

Summary

InnateDB Protein

IDBP-127724.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rbmy1a1

Protein Name

RNA binding motif protein, Y chromosome, family 1, member A1

Synonyms

RBM; Rbm1; Rbm1-rs1; Rbmy1a1; Rbmy1a1-rs1; Rbmy1b;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000097930

InnateDB Gene

IDBG-731009 (Rbmy1a1)

Protein Structure

UniProt Annotation

Function

RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Testis-specific. {ECO:0000269PubMed:9499427}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003729	mRNA binding

Biological Process

GO:0000381	regulation of alternative mRNA splicing, via spliceosome
GO:0006397	mRNA processing
GO:0008380	RNA splicing

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:104732

InterPro

IPR000504 RNA recognition motif domain

PFAM

PF00076

PRINTS

PIRSF

SMART

SM00360

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O35698

PhosphoSite

PhosphoSite-O35698

TrEMBL

UniProt Splice Variant

Entrez Gene

19657

UniGene

Mm.4711

RefSeq

NP_035383

MGI ID

MGI Symbol

Rbmy

OMIM

CCDS

CCDS30546

HPRD

IMGT

EMBL

AC132601 Y15131

GenPept

CAA75403