InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bambi

Summary

InnateDB Protein

IDBP-127780.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bambi

Protein Name

BMP and activin membrane-bound inhibitor, homolog (Xenopus laevis)

Synonyms

2610003H06Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025075

InnateDB Gene

IDBG-127778 (Bambi)

Protein Structure

UniProt Annotation

Function

Negatively regulates TGF-beta signaling. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004675	transmembrane receptor protein serine/threonine kinase activity
GO:0005024	transforming growth factor beta-activated receptor activity
GO:0005109	frizzled binding

Biological Process

GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0008284	positive regulation of cell proliferation
GO:0008360	regulation of cell shape
GO:0010718	positive regulation of epithelial to mesenchymal transition
GO:0016477	cell migration
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032092	positive regulation of protein binding
GO:0035413	positive regulation of catenin import into nucleus
GO:0045893	positive regulation of transcription, DNA-templated
GO:0090263	positive regulation of canonical Wnt signaling pathway