Version 5.4
| Mus musculus Protein: Mup14 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Protein | IDBP-128142.7 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | Mup14 | ||||||||||||
| Protein Name | major urinary protein 17 | ||||||||||||
| Synonyms | |||||||||||||
| Species | Mus musculus | ||||||||||||
| Ensembl Protein | ENSMUSP00000064072 | ||||||||||||
| InnateDB Gene | IDBG-152342 (Mup14) | ||||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||||
| Function | Major urinary proteins (Mups) bind pheromones, thus stabilize them and allow slow release into the air from urine marks. May protect pheromones from oxidation. May also act as pheromones themselves. In this context, they play a role in the regulation of social behaviors, such as aggression, mating, pup- suckling, territory establishment and dominance (By similarity). {ECO:0000250}. | ||||||||||||
| Subcellular Localization | Secreted {ECO:0000250}. | ||||||||||||
| Disease Associations | |||||||||||||
| Tissue Specificity | Because of their involvement in the coordination of social behavior, Mup proteins are thought to exhibit variable expression depending upon gender, age and status of the studied individuals. Expression may also be strain- specific: in strains C57BL/6J and 129S7, transcriptional support is lacking for Mup17. {ECO:0000269PubMed:18507838}. | ||||||||||||
| Comments | |||||||||||||
| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||||
| PDB ID | MGI:3702005 | ||||||||||||
| InterPro |
IPR000566
Lipocalin/cytosolic fatty-acid binding domain IPR002345 Lipocalin IPR002448 Odour-binding protein IPR002968 Alpha-1-microglobulin IPR002971 Major urinary protein IPR002972 Prostaglandin D synthase IPR011038 Calycin-like |
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| PFAM |
PF00061
PF08212 |
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| PRINTS |
PR00179
PR01173 PR01215 PR01221 PR01254 |
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| PIRSF | |||||||||||||
| SMART | |||||||||||||
| TIGRFAMs | |||||||||||||
| Post-translational Modifications | |||||||||||||
| Modification | |||||||||||||
| Cross-References | |||||||||||||
| SwissProt | |||||||||||||
| PhosphoSite | PhosphoSite-B5X0G2 | ||||||||||||
| TrEMBL | A2CEK7 | ||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 100039116 | ||||||||||||
| UniGene | |||||||||||||
| RefSeq | |||||||||||||
| MGI ID | |||||||||||||
| MGI Symbol | Mup14 | ||||||||||||
| OMIM | |||||||||||||
| CCDS | CCDS51195 | ||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| EMBL | BK006659 BX950196 CR550303 | ||||||||||||
| GenPept | DAA06308 | ||||||||||||