Version 5.4
Mus musculus Protein: Dlx6
Summary
InnateDB Protein IDBP-128246.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dlx6
Protein Name distal-less homeobox 6
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000031768
InnateDB Gene IDBG-128244 (Dlx6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0030326 embryonic limb morphogenesis
GO:0030855 epithelial cell differentiation
GO:0042472 inner ear morphogenesis
GO:0048646 anatomical structure formation involved in morphogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0060021 palate development
GO:0060322 head development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:101927
InterPro IPR000047 Helix-turn-helix motif
IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR00031
PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P70397
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 13396
UniGene Mm.439763
RefSeq
MGI ID
MGI Symbol Dlx6
OMIM
CCDS
HPRD
IMGT
EMBL AC122240 AF022078 BC114342 EF535989 U67841
GenPept AAB94583 AAC52844 AAI14343 ABQ10645

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca