Version 5.4
Mus musculus Protein: Ubxn2b
Summary
InnateDB Protein IDBP-128562.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ubxn2b
Protein Name UBX domain protein 2B
Synonyms 3110003A22Rik; 6430407D20Rik; AI451665; p37;
Species Mus musculus
Ensembl Protein ENSMUSP00000029907
InnateDB Gene IDBG-128560 (Ubxn2b)
Protein Structure
UniProt Annotation
Function Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:1915303
InterPro IPR001012 UBX domain
IPR012989 SEP domain
IPR029071 Ubiquitin-related domain
PFAM PF00789
PF08059
PRINTS
PIRSF
SMART SM00166
SM00553
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0KL01
PhosphoSite PhosphoSite-Q0KL01
TrEMBL
UniProt Splice Variant
Entrez Gene 68053
UniGene Mm.475278
RefSeq NP_080810
MGI ID
MGI Symbol Ubxn2b
OMIM
CCDS CCDS17949
HPRD
IMGT
EMBL AB120715 AK012822 AK028268 AK032332 AK049018 AL772385 BC076632
GenPept AAH76632 BAB28494 BAC25851 BAC27819 BAC33515 BAF30880 CAM21532

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca