InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gstp2

Summary

InnateDB Protein

IDBP-128819.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gstp2

Protein Name

glutathione S-transferase, pi 2

Synonyms

Gst-3; Gst3; GSTpiA;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000038931

InnateDB Gene

IDBG-128817 (Gstp2)

Protein Structure

UniProt Annotation

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Cannot metabolize 1-chloro-2,4-dinitrobenzene.

Subcellular Localization

Disease Associations

Tissue Specificity

Selectively expressed in gall bladder, colon, heart, and skeletal muscle.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004364	glutathione transferase activity
GO:0005515	protein binding

Biological Process

GO:0006749

glutathione metabolic process

Cellular Component

Protein Structure and Domains

PDB ID

MGI:95864

InterPro

IPR003082 Glutathione S-transferase, Pi class
IPR004045 Glutathione S-transferase, N-terminal
IPR004046 Glutathione S-transferase, C-terminal
IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold

PFAM