Version 5.4
| Mus musculus Protein: Clvs1 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Protein | IDBP-128891.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Clvs1 | ||||||||
| Protein Name | clavesin 1 | ||||||||
| Synonyms | 4933402J24Rik; Clvl1; Rlbp1l1; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000035649 | ||||||||
| InnateDB Gene | IDBG-128889 (Clvs1) | ||||||||
| Protein Structure |
|
||||||||
| UniProt Annotation | |||||||||
| Function | Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Early endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1921688 | ||||||||
| InterPro |
IPR001071
Cellular retinaldehyde binding/alpha-tocopherol transport IPR001251 CRAL-TRIO domain IPR011074 CRAL/TRIO, N-terminal domain |
||||||||
| PFAM |
PF00650
PF13716 PF03765 |
||||||||
| PRINTS |
PR00180
|
||||||||
| PIRSF | |||||||||
| SMART |
SM00516
SM01100 |
||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9D4C9 | ||||||||
| PhosphoSite | PhosphoSite-Q9D4C9 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 74438 | ||||||||
| UniGene | Mm.473368 | ||||||||
| RefSeq | NP_083216 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Clvs1 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS17957 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK016622 AK043072 AK084350 AK136083 AL671970 AL844180 BC062923 BC100556 | ||||||||
| GenPept | AAH62923 AAI00557 BAB30342 BAC31451 BAC39166 BAE22811 CAM15541 CAM23455 | ||||||||