Version 5.4
| Homo sapiens Protein: UNC13C | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-12895.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | UNC13C | ||||||||
| Protein Name | unc-13 homolog C (C. elegans) | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000260323 | ||||||||
| InnateDB Gene | IDBG-12893 (UNC13C) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | May play a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. May be involved in the regulation of synaptic transmission at parallel fiber - Purkinje cell synapses (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Localized to presynaptic structures. {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Exclusively expressed in brain. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000008
C2 domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain IPR010439 Calcium-dependent secretion activator IPR019558 Mammalian uncoordinated homology 13, subgroup, domain 2 |
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| PFAM |
PF00168
PF00130 PF06292 PF10540 |
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| PRINTS |
PR00360
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| PIRSF | |||||||||
| SMART |
SM00239
SM00109 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8NB66 | ||||||||
| PhosphoSite | PhosphoSite-Q8NB66 | ||||||||
| TrEMBL | H3BRP8 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 440279 | ||||||||
| UniGene | Hs.657273 | ||||||||
| RefSeq | NP_001074003 | ||||||||
| HUGO | HGNC:23149 | ||||||||
| OMIM | 614568 | ||||||||
| CCDS | CCDS45264 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AC010867 AC022302 AC034103 AC068711 AK054981 AK091491 AL834407 BC040740 | ||||||||
| GenPept | AAH40740 BAB70836 BAC03675 CAD39069 | ||||||||