Mus musculus Protein: Mycn
Summary
InnateDB Protein IDBP-128964.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mycn
Protein Name v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
Synonyms bHLHe37; c-nmyc; N-myc; Nmyc; Nmyc-1; Nmyc1;
Species Mus musculus
Ensembl Protein ENSMUSP00000045993
InnateDB Gene IDBG-128962 (Mycn)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 8 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0001502 cartilage condensation
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0006355 regulation of transcription, DNA-templated
GO:0008284 positive regulation of cell proliferation
GO:0010942 positive regulation of cell death
GO:0030324 lung development
GO:0042733 embryonic digit morphogenesis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048704 embryonic skeletal system morphogenesis
GO:0048712 negative regulation of astrocyte differentiation
GO:0048754 branching morphogenesis of an epithelial tube
GO:2000378 negative regulation of reactive oxygen species metabolic process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:97357
InterPro IPR002418 Transcription regulator Myc
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
IPR012682 Transcription regulator Myc, N-terminal
PFAM PF00010
PF01056
PRINTS PR00044
PIRSF PIRSF001705
SMART SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P03966
PhosphoSite PhosphoSite-P03966
TrEMBL Q810L7
UniProt Splice Variant
Entrez Gene 18109
UniGene Mm.400380
RefSeq NP_032735
MGI ID
MGI Symbol Mycn
OMIM
CCDS CCDS25818
HPRD
IMGT
EMBL AK146696 AK146913 BC049783 CH466582 M12731 M29208 M36277 X03919 X06993
GenPept AAA39788 AAA39830 AAA39833 AAH49783 BAE27366 BAE27525 CAA27557 EDK98450