InnateDB Protein
|
IDBP-129041.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Ugt3a1
|
Protein Name
|
UDP glycosyltransferases 3 family, polypeptide A1
|
Synonyms
|
AI746432;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000022861
|
InnateDB Gene
|
IDBG-129039 (Ugt3a1)
|
Protein Structure
|
|
Function |
UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
Disease Associations |
|
Tissue Specificity |
Highly expressed in kidney, while it is expressed at low levels in liver. Not detected in other tissues examined. {ECO:0000269PubMed:17050650}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:2146055
|
InterPro |
IPR002213
UDP-glucuronosyl/UDP-glucosyltransferase
IPR007235
Glycosyl transferase, family 28, C-terminal
|
PFAM |
PF00201
PF04101
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q3UP75
|
PhosphoSite |
PhosphoSite-Q3UP75
|
TrEMBL |
H3BLE9
|
UniProt Splice Variant |
|
Entrez Gene |
105887
|
UniGene |
Mm.482274
|
RefSeq |
NP_997099
|
MGI ID |
|
MGI Symbol |
Ugt3a1
|
OMIM |
|
CCDS |
CCDS27374
|
HPRD |
|
IMGT |
|
EMBL |
AC132893
AK143745
BC025940
|
GenPept |
AAH25940
BAE25522
|
|
|