InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mefv

Summary

InnateDB Protein

IDBP-129151.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Mefv

Protein Name

Mediterranean fever

Synonyms

FMF; pyrin; TRIM20;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000097795

InnateDB Gene

IDBG-129147 (Mefv)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0008270	zinc ion binding

Biological Process

GO:0006954	inflammatory response
GO:0032691	negative regulation of interleukin-1 beta production
GO:0032695	negative regulation of interleukin-12 production
GO:0050728	negative regulation of inflammatory response
GO:0071641	negative regulation of macrophage inflammatory protein 1 alpha production
GO:2001056	positive regulation of cysteine-type endopeptidase activity