Mus musculus Protein: Nat15 | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-129262.7 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Nat15 | ||||||||||||
Protein Name | N-acetyltransferase 15 (GCN5-related, putative) | ||||||||||||
Synonyms | 1200013P24Rik; AI315146; Nat15; | ||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Protein | ENSMUSP00000006138 | ||||||||||||
InnateDB Gene | IDBG-129260 (Nat15) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | Histone acetyltransferase localized in the Golgi apparatus that mediates acetylation of free histone H4, thereby facilitating nucleosome assembly. Has a preference for free histone H4 'Lys-20'(H4K20ac), 'Lys-79'(H4K79ac) and 'Lys-91' (H4K91ac). Also displays alpha (N-terminal) acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase (By similarity). {ECO:0000250}. | ||||||||||||
Subcellular Localization | Golgi apparatus membrane {ECO:0000250}. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | |||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | MGI:1922013 | ||||||||||||
InterPro |
IPR000182
GNAT domain IPR013653 FR47-like IPR016181 Acyl-CoA N-acyltransferase |
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PFAM |
PF00583
PF13302 PF13508 PF13673 PF13718 PF08445 |
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PRINTS | |||||||||||||
PIRSF | |||||||||||||
SMART | |||||||||||||
TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | Q9DBU2 | ||||||||||||
PhosphoSite | PhosphoSite-Q9DBU2 | ||||||||||||
TrEMBL | H3BIY0 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 74763 | ||||||||||||
UniGene | Mm.28403 | ||||||||||||
RefSeq | XP_006522743 | ||||||||||||
MGI ID | |||||||||||||
MGI Symbol | Naa60 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS37239 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | AC129021 AK004750 AK088736 BC004837 | ||||||||||||
GenPept | AAH04837 BAB23531 BAC40538 | ||||||||||||