Version 5.4
Mus musculus Protein: Larp4b
Summary
InnateDB Protein IDBP-129284.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Larp4b
Protein Name La ribonucleoprotein domain family, member 4B
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000089437
InnateDB Gene IDBG-129282 (Larp4b)
Protein Structure
UniProt Annotation
Function Stimulates mRNA translation. {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000250}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs in response to arsenite treatment. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
Biological Process
GO:0045727 positive regulation of translation
Cellular Component
GO:0005829 cytosol
GO:0010494 cytoplasmic stress granule
GO:0042788 polysomal ribosome
Protein Structure and Domains
PDB ID MGI:106330
InterPro IPR006630 RNA-binding protein Lupus La
PFAM PF05383
PRINTS
PIRSF
SMART SM00715
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6A0A2
PhosphoSite PhosphoSite-Q6A0A2
TrEMBL
UniProt Splice Variant
Entrez Gene 217980
UniGene Mm.485517
RefSeq XP_006516541
MGI ID
MGI Symbol Larp4b
OMIM
CCDS
HPRD
IMGT
EMBL AK042491 AK080953 AK160759 AK172916 BC078640
GenPept AAH78640 BAC31273 BAC38091 BAD32194 BAE35994

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca