Version 5.4
Mus musculus Protein: Brix1
Summary
InnateDB Protein IDBP-129373.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Brix1
Protein Name BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
Synonyms 1110064N10Rik; Bxdc2; C76935;
Species Mus musculus
Ensembl Protein ENSMUSP00000022855
InnateDB Gene IDBG-129371 (Brix1)
Protein Structure
UniProt Annotation
Function Required for biogenesis of the 60S ribosomal subunit. {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0008150 biological_process
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID MGI:1915082
InterPro IPR004154 Anticodon-binding
IPR007109 Brix domain
PFAM PF03129
PF04427
PRINTS
PIRSF
SMART SM00879
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DCA5
PhosphoSite PhosphoSite-Q9DCA5
TrEMBL Q8CEX3
UniProt Splice Variant
Entrez Gene 67832
UniGene Mm.28057
RefSeq NP_080672
MGI ID
MGI Symbol Brix1
OMIM
CCDS CCDS37042
HPRD
IMGT
EMBL AK002985 AK010171 AK168325 BC014832
GenPept AAH14832 BAB22497 BAC25283 BAE40264

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca