Version 5.4
Mus musculus Protein: Praf2
Summary
InnateDB Protein IDBP-129391.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Praf2
Protein Name PRA1 domain family 2
Synonyms AA986329; C78013; DXImx39e; JM4; Sfc20;
Species Mus musculus
Ensembl Protein ENSMUSP00000033489
InnateDB Gene IDBG-129389 (Praf2)
Protein Structure
UniProt Annotation
Function May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis (By similarity). {ECO:0000250}.
Subcellular Localization Endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0015031 protein transport
Cellular Component
GO:0005575 cellular_component
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1859607
InterPro IPR004895 Prenylated rab acceptor PRA1
PFAM PF03208
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JIG8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 54637
UniGene Mm.396573
RefSeq NP_613068
MGI ID
MGI Symbol Praf2
OMIM
CCDS CCDS29971
HPRD
IMGT
EMBL AF229636 AK003344 BC064757
GenPept AAF66950 AAH64757 BAB22729

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca