Version 5.4
Mus musculus Protein: Rxfp3
Summary
InnateDB Protein IDBP-129583.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rxfp3
Protein Name relaxin family peptide receptor 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000062741
InnateDB Gene IDBG-129581 (Rxfp3)
Protein Structure
UniProt Annotation
Function Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0008528 G-protein coupled peptide receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0032467 positive regulation of cytokinesis
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2441827
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BGE9
PhosphoSite PhosphoSite-Q8BGE9
TrEMBL Q5Y988
UniProt Splice Variant
Entrez Gene 239336
UniGene Mm.209312
RefSeq NP_848832
MGI ID
MGI Symbol Rxfp3
OMIM
CCDS CCDS27383
HPRD
IMGT
EMBL AK043414 AK046367 AK084001 AY170825 AY633762 BC053073 CH466581
GenPept AAH53073 AAO17677 AAU93888 BAC31542 BAC32691 BAC39091 EDL03286

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca