Mus musculus Protein: Dsg1c
Summary
InnateDB Protein IDBP-129741.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dsg1c
Protein Name desmoglein 1 gamma
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000054799
InnateDB Gene IDBG-129739 (Dsg1c)
Protein Structure
UniProt Annotation
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, desmosome.
Disease Associations
Tissue Specificity Expressed in epidermis, brain, liver, skeletal, muscle and testis. {ECO:0000269PubMed:12631243, ECO:0000269PubMed:12787123}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030057 desmosome
Protein Structure and Domains
PDB ID MGI:2664358
InterPro IPR000233 Cadherin, cytoplasmic domain
IPR002126 Cadherin
IPR009123 Desmoglein
IPR015919 Cadherin-like
PFAM PF01049
PF00028
PRINTS PR00205
PR01819
PIRSF
SMART SM00112
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TSF0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 211924
UniGene Mm.391118
RefSeq NP_859008
MGI ID
MGI Symbol Dsg1c
OMIM
CCDS CCDS29079
HPRD
IMGT
EMBL AY192159 AY314983
GenPept AAP31153 AAP79926