Version 5.4
| Mus musculus Protein: Dsg1b | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-129840.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Dsg1b | ||||||||
| Protein Name | desmoglein 1 beta | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000076026 | ||||||||
| InnateDB Gene | IDBG-129838 (Dsg1b) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | ||||||||
| Subcellular Localization | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, desmosome {ECO:0000269PubMed:12631242}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in epidermis. {ECO:0000269PubMed:12631242, ECO:0000269PubMed:12787123}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2664357 | ||||||||
| InterPro |
IPR000233
Cadherin, cytoplasmic domain IPR002126 Cadherin IPR009122 Desmosomal cadherin IPR009123 Desmoglein IPR015919 Cadherin-like |
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| PFAM |
PF01049
PF00028 |
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| PRINTS |
PR00205
PR01818 PR01819 |
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| PIRSF | |||||||||
| SMART |
SM00112
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q7TSF1 | ||||||||
| PhosphoSite | PhosphoSite-Q7TSF1 | ||||||||
| TrEMBL | B2RQH0 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 225256 | ||||||||
| UniGene | Mm.269128 | ||||||||
| RefSeq | NP_859010 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Dsg1b | ||||||||
| OMIM | |||||||||
| CCDS | CCDS29081 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AY192158 AY315940 BC137927 CH466557 | ||||||||
| GenPept | AAI37928 AAP31152 AAP80571 EDK96947 | ||||||||