InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rbm4b

Summary

InnateDB Protein

IDBP-129866.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rbm4b

Protein Name

RNA binding motif protein 4B

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000038256

InnateDB Gene

IDBG-129864 (Rbm4b)

Protein Structure

UniProt Annotation

Function

Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA. {ECO:0000269PubMed:17264215}.

Subcellular Localization

Nucleus, nucleolus {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in the suprachiasmatic nucleus (SCN) (at protein level). Expressed in the suprachiasmatic nucleus (SCN). {ECO:0000269PubMed:17264215}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006397	mRNA processing
GO:0006417	regulation of translation
GO:0007623	circadian rhythm
GO:0008380	RNA splicing
GO:0010628	positive regulation of gene expression
GO:0032922	circadian regulation of gene expression
GO:0043153	entrainment of circadian clock by photoperiod