Mus musculus Protein: Ccs
Summary
InnateDB Protein IDBP-129976.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccs
Protein Name copper chaperone for superoxide dismutase
Synonyms Ccsd;
Species Mus musculus
Ensembl Protein ENSMUSP00000035486
InnateDB Gene IDBG-129974 (Ccs)
Protein Structure
UniProt Annotation
Function Delivers copper to copper zinc superoxide dismutase (SOD1).
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004784 superoxide dismutase activity
GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006801 superoxide metabolic process
GO:0019430 removal of superoxide radicals
GO:0030001 metal ion transport
GO:0051353 positive regulation of oxidoreductase activity
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1333783
InterPro IPR001424 Superoxide dismutase, copper/zinc binding domain
IPR006121 Heavy metal-associated domain, HMA
PFAM PF00080
PF00403
PRINTS PR00068
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9WU84
PhosphoSite PhosphoSite-Q9WU84
TrEMBL Q543K2
UniProt Splice Variant
Entrez Gene 12460
UniGene Mm.434411
RefSeq NP_058588
MGI ID
MGI Symbol Ccs
OMIM
CCDS CCDS29438
HPRD
IMGT
EMBL AF121906 AF173379 AK010264 AK050072 BC026938 CH466612
GenPept AAD23832 AAF70242 AAH26938 BAB26806 BAC34057 EDL33071