Version 5.4
Mus musculus Protein: Ipcef1
Summary
InnateDB Protein IDBP-130045.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ipcef1
Protein Name interaction protein for cytohesin exchange factors 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000077215
InnateDB Gene IDBG-130039 (Ipcef1)
Protein Structure
UniProt Annotation
Function Enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 in a concentration-dependent manner. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocated with PSCD2 to the plasma membrane upon epidermal growth factor (EGF) stimulation. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:2444159
InterPro IPR001849 Pleckstrin homology domain
PFAM PF00169
PRINTS
PIRSF
SMART SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5DU31
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 320495
UniGene Mm.487015
RefSeq NP_001164272
MGI ID
MGI Symbol Ipcef1
OMIM
CCDS
HPRD
IMGT
EMBL AC155718 AC164171 AK038257 AK157384 AK220339
GenPept BAC29953 BAD90405 BAE34075

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca