Version 5.4
Mus musculus Protein: Tmem55a
Summary
InnateDB Protein IDBP-130318.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmem55a
Protein Name transmembrane protein 55A
Synonyms 2610319K07Rik; AI315591; AV001360;
Species Mus musculus
Ensembl Protein ENSMUSP00000029875
InnateDB Gene IDBG-130316 (Tmem55a)
Protein Structure
UniProt Annotation
Function Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4- bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3- monophosphate (By similarity). {ECO:0000250}.
Subcellular Localization Late endosome membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Lysosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016787 hydrolase activity
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005765 lysosomal membrane
GO:0016021 integral component of membrane
GO:0031902 late endosome membrane
Protein Structure and Domains
PDB ID MGI:1919769
InterPro IPR019178 Transmembrane protein 55A/B
PFAM PF09788
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CZX7
PhosphoSite PhosphoSite-Q9CZX7
TrEMBL
UniProt Splice Variant
Entrez Gene 72519
UniGene Mm.279158
RefSeq NP_082540
MGI ID
MGI Symbol Tmem55a
OMIM
CCDS CCDS17981
HPRD
IMGT
EMBL AK012054 AK033845 AK049213 BC021435
GenPept AAH21435 BAB27995 BAC28493 BAC33613

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca