Version 5.4
| Mus musculus Protein: Gpr37 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-130382.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Gpr37 | ||||||||
| Protein Name | G protein-coupled receptor 37 | ||||||||
| Synonyms | AI848630; Pael-R; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000052185 | ||||||||
| InnateDB Gene | IDBG-130380 (Gpr37) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1313297 | ||||||||
| InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like IPR003909 G protein-coupled receptor 37 orphan IPR017452 GPCR, rhodopsin-like, 7TM |
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| PFAM |
PF00001
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| PRINTS |
PR00237
PR01421 |
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9QY42 | ||||||||
| PhosphoSite | PhosphoSite-Q9QY42 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 14763 | ||||||||
| UniGene | Mm.457590 | ||||||||
| RefSeq | NP_034468 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Gpr37 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS19949 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF132039 AJ223305 AJ223834 AJ223835 AK032525 AK044508 AK053287 BC031918 | ||||||||
| GenPept | AAF22144 AAH31918 BAC27911 BAC31956 BAC35333 CAA11247 CAA11579 | ||||||||