Version 5.4
Mus musculus Protein: Acot10
Summary
InnateDB Protein IDBP-130669.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Acot10
Protein Name acyl-CoA thioesterase 10
Synonyms Acate3; MT-ACT48; p48;
Species Mus musculus
Ensembl Protein ENSMUSP00000051333
InnateDB Gene IDBG-130667 (Acot10)
Protein Structure
UniProt Annotation
Function Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs. {ECO:0000305}.
Subcellular Localization Mitochondrion {ECO:0000269PubMed:10383425, ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0047617 acyl-CoA hydrolase activity
Biological Process
GO:0006637 acyl-CoA metabolic process
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:1928940
InterPro IPR029069 HotDog domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q32MW3
PhosphoSite PhosphoSite-Q32MW3
TrEMBL
UniProt Splice Variant
Entrez Gene 64833
UniGene Mm.352763
RefSeq NP_073727
MGI ID
MGI Symbol Acot10
OMIM
CCDS CCDS27395
HPRD
IMGT
EMBL AJ238894 BC108959 BC108960 EF014736
GenPept AAI08960 AAI08961 ABK20321 CAB45255

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca