Version 5.4
Mus musculus Protein: Tpd52
Summary
InnateDB Protein IDBP-130795.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tpd52
Protein Name tumor protein D52
Synonyms AI043038; mD52;
Species Mus musculus
Ensembl Protein ENSMUSP00000088913
InnateDB Gene IDBG-130793 (Tpd52)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Isoform 2 is expressed at higher levels in kidney and brain than in liver, lung, testis and heart. Within the brain, isoform 2 is highly expressed in the granular layer of the cerebellum, the cortex and the hippocampus. In embryos, isoform 2 is expressed in the epithelium of the developing intestine, stomach, olfactory epithelium, neuronal layers of the retina, salivary gland, kidney and dorsal root ganglion. {ECO:0000269PubMed:8632896}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008284 positive regulation of cell proliferation
GO:0030183 B cell differentiation
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:107749
InterPro IPR007327 Tumour protein D52
PFAM PF04201
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q62393
PhosphoSite PhosphoSite-Q62393
TrEMBL D3Z637
UniProt Splice Variant
Entrez Gene 21985
UniGene Mm.465501
RefSeq NP_001020433
MGI ID
MGI Symbol Tpd52
OMIM
CCDS CCDS38386
HPRD
IMGT
EMBL AC133935 AC161056 AK005456 AK032111 AK151471 AK151744 AK152543 AK153266 AK153292 AK161753 AK168379 AK168817 AK169751 AK170725 AK171050 AY048852 BC002036 BC004068 BC094018 CH466577 U44426
GenPept AAB40897 AAH02036 AAH04068 AAH94018 AAL05266 BAB24048 BAC27709 BAE30428 BAE30655 BAE31298 BAE31856 BAE31875 BAE36558 BAE40308 BAE40644 BAE41345 BAE41982 BAE42212 EDL05192 EDL05193

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca