InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Myo10

Summary

InnateDB Protein

IDBP-130906.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Myo10

Protein Name

myosin X

Synonyms

AW048724; D15Ertd600e; mKIAA0799;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000022882

InnateDB Gene

IDBG-130902 (Myo10)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	5 [view]
Protein-DNA	2 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030507	spectrin binding

Biological Process

GO:0007165	signal transduction
GO:0008360	regulation of cell shape
GO:0022409	positive regulation of cell-cell adhesion
GO:0048870	cell motility
GO:0051489	regulation of filopodium assembly

Cellular Component

GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0030175	filopodium
GO:0043005	neuron projection
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

MGI:107716

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR000159 Ras-association
IPR000299 FERM domain
IPR000857 MyTH4 domain
IPR001849 Pleckstrin homology domain
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR029071 Ubiquitin-related domain

PFAM

PF00612
PF00788
PF00784
PF00169
PF00373

PRINTS

PIRSF

SMART

SM00015
SM00314
SM00139
SM00233
SM00295

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite