Version 5.4
Mus musculus Protein: Hilpda
Summary
InnateDB Protein IDBP-131079.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hilpda
Protein Name RIKEN cDNA 2310016C08 gene
Synonyms 2310016C08Rik; AW049004; Hig2;
Species Mus musculus
Ensembl Protein ENSMUSP00000060791
InnateDB Gene IDBG-131077 (Hilpda)
Protein Structure
UniProt Annotation
Function Increases intracellular lipid accumulation. Stimulates expression of cytokines including IL6, MIF and VEGFA. Enhances cell growth and proliferation (By similarity). {ECO:0000250}.
Subcellular Localization Lipid droplet {ECO:0000250}. Secreted {ECO:0000250}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
Biological Process
GO:0001819 positive regulation of cytokine production
GO:0006950 response to stress
GO:0008284 positive regulation of cell proliferation
GO:0010884 positive regulation of lipid storage
GO:0035425 autocrine signaling
Cellular Component
GO:0005615 extracellular space
GO:0005811 lipid particle
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0030141 secretory granule
Protein Structure and Domains
PDB ID MGI:1916823
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JLS0
PhosphoSite PhosphoSite-Q9JLS0
TrEMBL
UniProt Splice Variant
Entrez Gene 69573
UniGene Mm.45161
RefSeq NP_076005
MGI ID
MGI Symbol Hilpda
OMIM
CCDS CCDS39450
HPRD
IMGT
EMBL AF141311 AK009377 AK144676 BC020081 BC083056
GenPept AAF25720 AAH20081 AAH83056 BAB26253 BAE26005

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca