InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Alg1

Summary

InnateDB Protein

IDBP-131137.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Alg1

Protein Name

asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000046534

InnateDB Gene

IDBG-131133 (Alg1)

Protein Structure

UniProt Annotation

Function

Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER (By similarity). {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0004578	chitobiosyldiphosphodolichol beta-mannosyltransferase activity

Biological Process

GO:0006486	protein glycosylation
GO:0008150	biological_process
GO:0009058	biosynthetic process
GO:0097502	mannosylation

Cellular Component

GO:0005575	cellular_component
GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2384774

InterPro

IPR001296 Glycosyl transferase, family 1

PFAM

PF00534

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q921Q3

PhosphoSite

PhosphoSite-Q921Q3

TrEMBL

UniProt Splice Variant

Entrez Gene

208211

UniGene

Mm.34581

RefSeq

MGI ID

MGI Symbol

Alg1

OMIM

CCDS

HPRD

IMGT

EMBL

AK145871 BC011281

GenPept

BAE26713