Version 5.4
Mus musculus Protein: Gal3st3
Summary
InnateDB Protein IDBP-131221.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gal3st3
Protein Name galactose-3-O-sulfotransferase 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000061517
InnateDB Gene IDBG-131219 (Gal3st3)
Protein Structure
UniProt Annotation
Function Transfers a sulfate to position 3 of non-reducing beta- galactosyl residues in N-glycans and core2-branched O-glycans. Has high activity towards Gal-beta-1,4-GlcNAc, Gal-beta-1,4(Fuc-alpha- 1,3)GlcNAc and lower activity towards Gal-beta-1,3(Fuc-alpha- 1,4)GlcNAc (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus, Golgi stack membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001733 galactosylceramide sulfotransferase activity
GO:0050694 galactose 3-O-sulfotransferase activity
Biological Process
GO:0009058 biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
Protein Structure and Domains
PDB ID MGI:3617843
InterPro IPR009729 Galactose-3-O-sulfotransferase
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF06990
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P61315
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 545276
UniGene Mm.447174
RefSeq NP_001019888
MGI ID
MGI Symbol Gal3st3
OMIM
CCDS CCDS29455
HPRD
IMGT
EMBL BC066996
GenPept AAH66996

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca