Version 5.4
Mus musculus Protein: Abhd6
Summary
InnateDB Protein IDBP-131540.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Abhd6
Protein Name abhydrolase domain containing 6
Synonyms 0610041D24Rik; AA673485; AV065425;
Species Mus musculus
Ensembl Protein ENSMUSP00000026313
InnateDB Gene IDBG-131538 (Abhd6)
Protein Structure
UniProt Annotation
Function Has 2-arachidonoylglycerol hydrolase activity. May be a regulator of endocannabinoid signaling pathways. {ECO:0000269PubMed:18096503}.
Subcellular Localization Membrane {ECO:0000269PubMed:18096503}; Single-pass type II membrane protein {ECO:0000269PubMed:18096503}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0047372 acylglycerol lipase activity
Biological Process
GO:0008152 metabolic process
GO:0030336 negative regulation of cell migration
GO:0060292 long term synaptic depression
GO:2000124 regulation of endocannabinoid signaling pathway
Cellular Component
GO:0005739 mitochondrion
GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
Protein Structure and Domains
PDB ID MGI:1913332
InterPro IPR000073 Alpha/beta hydrolase fold-1
IPR000639 Epoxide hydrolase-like
IPR013818 Lipase, N-terminal
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00561
PF00151
PRINTS PR00111
PR00412
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R2Y0
PhosphoSite PhosphoSite-Q8R2Y0
TrEMBL Q9D375
UniProt Splice Variant
Entrez Gene 66082
UniGene Mm.401538
RefSeq XP_006518138
MGI ID
MGI Symbol Abhd6
OMIM
CCDS CCDS26808
HPRD
IMGT
EMBL AK002883 AK018260 AK076105 AK090076 AK168782 BC027011
GenPept AAH27011 BAB22430 BAB31136 BAC36186 BAC41081 BAE40616

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca