Version 5.4
Homo sapiens Protein: PYGO1
Summary
InnateDB Protein IDBP-13167.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PYGO1
Protein Name pygopus homolog 1 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000302327
InnateDB Gene IDBG-13165 (PYGO1)
Protein Structure
UniProt Annotation
Function Involved in signal transduction through the Wnt pathway.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0001822 kidney development
GO:0002244 hematopoietic progenitor cell differentiation
GO:0007286 spermatid development
GO:0007289 spermatid nucleus differentiation
GO:0009791 post-embryonic development
GO:0016055 Wnt signaling pathway
GO:0034504 protein localization to nucleus
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001965 Zinc finger, PHD-type
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger
PFAM PF00628
PRINTS
PIRSF
SMART SM00249
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y3Y4
PhosphoSite PhosphoSite-Q9Y3Y4
TrEMBL
UniProt Splice Variant
Entrez Gene 26108
UniGene Hs.87194
RefSeq NP_056432
HUGO HGNC:30256
OMIM 606902
CCDS CCDS10155
HPRD 06064
IMGT
EMBL AF457207 AL049925
GenPept AAL91370 CAB43209

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca