Mus musculus Protein: Colec11
Summary
InnateDB Protein IDBP-131983.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Colec11
Protein Name collectin sub-family member 11
Synonyms 1010001H16Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000049285
InnateDB Gene IDBG-131981 (Colec11)
Protein Structure
UniProt Annotation
Function Lectin that binds to various sugars including fucose and mannose. Has a higher affinity for fucose compared to mannose. Does not bind to glucose, N-acetylglucosamine and N- acetylgalactosamine. Binds to lipopolysaccharides (LPS). Involved in fundamental development serving as a guidance cue for neural crest cell migration (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Highly expressed in embryonic murine craniofacial cartilage, heart, bronchi, kidney and vertebral bodies. {ECO:0000269PubMed:21258343}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005537 mannose binding
GO:0030246 carbohydrate binding
Biological Process
GO:0007275 multicellular organismal development
GO:0008150 biological_process
GO:0032502 developmental process
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
GO:0005581 collagen trimer
Protein Structure and Domains
PDB ID MGI:1918943
InterPro IPR001304 C-type lectin
IPR008160 Collagen triple helix repeat
IPR016187 C-type lectin fold
PFAM PF00059
PF01391
PRINTS
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3SXB8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 71693
UniGene Mm.30724
RefSeq NP_082142
MGI ID
MGI Symbol Colec11
OMIM
CCDS CCDS36426
HPRD
IMGT
EMBL AK003121 BC104380 BC104381
GenPept AAI04381 AAI04382 BAB22581