Version 5.4
Mus musculus Protein: St18
Summary
InnateDB Protein IDBP-132079.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol St18
Protein Name suppression of tumorigenicity 18
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000042056
InnateDB Gene IDBG-132077 (St18)
Protein Structure
UniProt Annotation
Function Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2446700
InterPro IPR002515 Zinc finger, C2HC-type
IPR013681 Myelin transcription factor 1
PFAM PF01530
PF08474
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80TY4
PhosphoSite PhosphoSite-Q80TY4
TrEMBL Q148A0
UniProt Splice Variant
Entrez Gene 240690
UniGene Mm.417411
RefSeq XP_006495564
MGI ID
MGI Symbol St18
OMIM
CCDS CCDS14810
HPRD
IMGT
EMBL AC091455 AC120544 AC162866 AJ536155 AK122303 AK133743 AK137440 AK141513 AK147320 AK147664 BC032273 BC118528 CH466536
GenPept AAH32273 AAI18529 BAC65585 BAE21817 BAE23351 BAE24709 BAE27844 BAE28057 CAD60089 EDL14264

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca