InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ovol1

Summary

InnateDB Protein

IDBP-132082.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ovol1

Protein Name

OVO homolog-like 1 (Drosophila)

Synonyms

BB147136; movo1; Ovo1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025861

InnateDB Gene

IDBG-132080 (Ovol1)

Protein Structure

UniProt Annotation

Function

Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system. {ECO:0000269PubMed:9808631}.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Expressed in skin, testis, kidney and weakly in lung. Not detected in heart, brain, spleen, liver and skeletal muscle.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001822	kidney development
GO:0006366	transcription from RNA polymerase II promoter
GO:0007010	cytoskeleton organization
GO:0007283	spermatogenesis
GO:0007498	mesoderm development
GO:0008544	epidermis development
GO:0009913	epidermal cell differentiation
GO:0043588	skin development
GO:0051729	germline cell cycle switching, mitotic to meiotic cell cycle
GO:1901994	negative regulation of meiotic cell cycle phase transition