Version 5.4
Mus musculus Protein: Emp2
Summary
InnateDB Protein IDBP-132205.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Emp2
Protein Name epithelial membrane protein 2
Synonyms XMP;
Species Mus musculus
Ensembl Protein ENSMUSP00000077466
InnateDB Gene IDBG-132203 (Emp2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005178 integrin binding
Biological Process
GO:0001954 positive regulation of cell-matrix adhesion
GO:2001046 positive regulation of integrin-mediated signaling pathway
Cellular Component
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
Protein Structure and Domains
PDB ID MGI:1098726
InterPro IPR003933 Epithelial membrane protein EMP-2
IPR004031 PMP-22/EMP/MP20/Claudin superfamily
IPR004032 PMP-22/EMP/MP20
IPR009944 Amastin surface glycoprotein
PFAM PF00822
PF13903
PF07344
PRINTS PR01455
PR01453
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O88662
PhosphoSite PhosphoSite-
TrEMBL Q548I4
UniProt Splice Variant
Entrez Gene 13731
UniGene Mm.246009
RefSeq NP_031955
MGI ID
MGI Symbol Emp2
OMIM
CCDS CCDS37250
HPRD
IMGT
EMBL AF083876 AF346627 CH466521
GenPept AAC33108 AAK29076 EDK97309

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca