InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ndufaf4

Summary

InnateDB Protein

IDBP-132420.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndufaf4

Protein Name

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4

Synonyms

1110007M04Rik; 3000003G13Rik; AW214064;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000029925

InnateDB Gene

IDBG-132418 (Ndufaf4)

Protein Structure

UniProt Annotation

Function

May be involved in cell proliferation and survival of hormone-dependent tumor cells. Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding
GO:0005516	calmodulin binding

Biological Process

GO:0010257	NADH dehydrogenase complex assembly
GO:0032981	mitochondrial respiratory chain complex I assembly

Cellular Component

GO:0005739	mitochondrion
GO:0031966	mitochondrial membrane

Protein Structure and Domains

PDB ID

MGI:1915743

InterPro

IPR009622 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

PFAM

PF06784

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D1H6

PhosphoSite

PhosphoSite-Q9D1H6

TrEMBL

UniProt Splice Variant

Entrez Gene

68493

UniGene

Mm.409731

RefSeq

NP_081018

MGI ID

MGI Symbol

Ndufaf4

OMIM

CCDS

CCDS18007

HPRD

IMGT

EMBL

AK003553 AK034728 AK160341 BC028764

GenPept

AAH28764 BAB22852 BAC28809 BAE35747