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InnateDB Protein
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IDBP-132513.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ufl1
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Protein Name
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RIKEN cDNA 1810074P20 gene
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Synonyms
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1810074P20Rik; AI429228; Kiaa0776; Maxer; mKIAA0776; Rcad;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000042118
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InnateDB Gene
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IDBG-132511 (Ufl1)
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Protein Structure
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| Function |
E3 UFM1-protein ligase that mediates ufmylation of target proteins such as DDRGK1. The function of ufmylation is unknown (By similarity). May act as a tumor suppressor by inhibiting cell invasion, blocking NF-kappa-B signaling and increasing stability of CDK5RAP3 (By similarity). {ECO:0000250}.
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| Subcellular Localization |
Endoplasmic reticulum {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=In cytoplasm colocalizes with CDK5RAP3. {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
9 [view]
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| PDB ID |
MGI:1914740
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| InterPro |
IPR018611
E3 UFM1-protein ligase 1
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| PFAM |
PF09743
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q8CCJ3
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
67490
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| UniGene |
Mm.487772
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
Ufl1
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
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| GenPept |
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Version 5.4